翻訳と辞書
Words near each other
・ Mir-216 microRNA precursor family
・ Mir-218 microRNA precursor family
・ Mir-219 microRNA precursor family
・ Mir-22
・ Mir-221 microRNA
・ Mir-223
・ MiR-224
・ Mir-23 microRNA precursor family
・ Mir-24 microRNA precursor family
・ Mir-241 microRNA precursor family
・ Mir-25 microRNA precursor family
・ Mir-26 microRNA precursor family
・ MiR-27
・ Mir-275 microRNA precursor family
・ Mir-277 microRNA precursor family
Mir-278 microRNA precursor family
・ Mir-279 microRNA precursor family
・ MiR-27b microRNA precursor
・ Mir-28 microRNA precursor family
・ Mir-281 microRNA precursor family
・ Mir-282 microRNA precursor family
・ Mir-29 microRNA precursor
・ MiR-296
・ Mir-299 microRNA precursor family
・ Mir-3 microRNA precursor family
・ Mir-30 microRNA precursor
・ Mir-301 microRNA precursor family
・ Mir-305 microRNA precursor family
・ Mir-31
・ Mir-3180 microRNA precursor family


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Mir-278 microRNA precursor family : ウィキペディア英語版
Mir-278 microRNA precursor family

In molecular biology mir-278 microRNA is a short RNA molecule belonging to a class of molecules referred to as microRNAs. These function to regulate the expression levels of other genes by several mechanisms, primarily binding to their target at its 3'UTR.
==Mis- and altered expression in ''Drosophila''==
miR-278 affects energy metabolism in the ''Drosophila Melanogaster'' species. Elevated insulin production has been observed in miR-278 mutants, due to insulin resistance in the absence of this microRNA. miR-278 is now known to act through regulation of the ''expanded'' gene transcript, and most likely through further miR-278 targets as well.〔 〕
Misexpression in the developing eye has been found to result in overgrowth, partially through apoptotic inhibition.〔 〕 There is a single base substitution which blocks the gain-of-function phenotype, indicating the acquisition of novel functions by misexpressed miRNAs which bring about unscheduled cell proliferation ''in vivo''. This is reflective of a microRNA potential in the promotion of tumour formation.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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